Initial research has shown that as we age function of the arteries feeding the brain declines, and reductions in brain blood flow and cognitive function occur. Research has also shown that exercise may promote healthy brain ageing, but we currently do not know how. This study will look at the function of arteries feeding the brain at rest and during handgrip exercise in adults.

Participant benefits:

As part of this study, you will get a full assessment of your blood pressure. You will also receive an ultrasound assessment of the structure and function of the vessels supplying and within the brain. You will also receive an assessment of nerve activity, which is an important regulator of your blood pressure. This study only requires 3-4 hours of your time, where you will gain a lot of insight into brain health and your cardiovascular function. 


  • Aged 19-90 years of age.
  • Have a BMI <35.
  • Not currently taking any anti-hypertensive medications.
  • Do not have a history of cardiovascular disease e.g. heart attack and stroke, or other diagnosed cardiovascular disease e.g. angina, coronary heart disease, carotid artery stenosis.

Register your interest:


This study has been approved by The University of Queensland Human Research Ethics Committee [Approval No. 2019001863]